Abstract
Massive osteolysis (Gorham's disease) first described by Jackson in 1838, is a rare disorder characterised by the spontaneous and progressive resorption of one or more of the skeletal bones. Any bone may be affected although there is predilection for the pelvis, humeral head, humeral shaft, axial skeleton and mandible. To date, 150 cases have been described in the literature, with fewer than 37 cases involving a maxillofacial site. Considering the rarity of the condition we have reported a case of massive osteolysis involving the mandible in a 41–year-old male patient, with a brief review of literature.
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