Abstract
1. 1. The application of new and derived methods of obtaining exfoliated and mechanically dislodged cells from all the combined surfaces of the oral cavity and examining them under ultraviolet light after staining with fluorescent dyes may provide a practical method whereby the practicing dentist can conduct a mass survey of the oral cavity for cancer as part of the routine oral examination. 2. 2. Rinsing of the oral cavity with physiologic saline solution, using tongue and tooth abrasion, has been demonstrated to provide a valid sample of cells from all areas of the oral cavity. 3. 3. A new instrument that will enable the clinician to obtain cells from the entire surface of a diffuse as well as a circumscribed lesion is described.
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