Abstract
The oceans harbor a great diversity of organisms, and have been recognized as an important source of new compounds with nutritional and therapeutic potential. Among these compounds, carbohydrate-based compounds are of particular interest because they exhibit numerous biological functions associated with their chemical diversity. This gives rise to new substances for the development of bioactive products. Many are the known applications of substances with glycosidic domains obtained from marine species. This review covers the structural properties and the current findings on the antioxidant, anti-inflammatory, anticoagulant, antitumor and antimicrobial activities of medium and high molecular-weight carbohydrates or glycosylated compounds extracted from various marine organisms.
Highlights
The oceans cover about 70% of the earth’s surface, and harbor a great diversity of living beings, ranging from unicellular bacteria to large multicellular mammals [1]
This study demonstrated the efficacy of alginate to seriousthe infections, mainly those caused by salmon uptakeresponsible control growth of Listeria monocytogenes, a bacterium for serious infections, mainly those caused by salmon uptake [39]
Sulfated polymannuronate (SPM), known as sulfated polymannuroguluronate, is a Sulfated polymannuronate (SPM), known as sulfated polymannuroguluronate, is a sulfated sulfated polysaccharide extracted from brown algae, rich in 4-linked β-D-manuronic acid (ManA) with a mean MW of polysaccharide extracted from brown algae, rich in 4-linked β-D-ManA with a mean MW of 10,000 Da
Summary
The oceans cover about 70% of the earth’s surface, and harbor a great diversity of living beings, ranging from unicellular bacteria to large multicellular mammals [1]. Some products obtained from marine sources are in the clinical trials phase for possible use as analgesics [4], anticancer drugs [5], and for treatments against viruses [6,7,8] Despite these studies, marine potential remains largely unknown. The main goal of this report is to reinforce to the scientific community the great value of marine-derived carbohydrates and glycosylated compounds of medium and high molecular-weight (MW) to drug discovery and development. Mar. Drugs 2018, 16, 233 actions on multiple systems, attention is paid more to their antioxidant, anti-inflammatory, anticoagulant, antitumor and antimicrobial properties. Present actions on multiple systems, attention is paid more to their antioxidant, anti-inflammatory, anticoagulant, and antimicrobial
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