Abstract
Brown tumor (BT) is nonneoplastic giant cell lesion that appears in advanced stages of hyperparathyroidism. It represents a giant cell reparative cellular phenomenon that involves areas with intense bone resorption because of high circulating parathyroid hormone (PTH) levels. A 27-year-old woman was referred with presentation of left mandibular swelling, mobility of teeth 33 and 34, and bleeding for 10 months, with an anatomopathologic diagnosis of central giant cells lesion. Orthopantomography showed bone involvement with a radiolucent image in the left mandibular body. Laboratory tests showed human parathyroid hormone (HPTH) and increased alkaline phosphatase, creatinine, and urea. Referral was made to endocrinology, which started pharmacotherapy and referred the patient for surgical removal of the left superior parathyroid. A diagnosis of parathyroid adenoma was made. The final diagnosis was a BT with central involvement. After resolution of the hyperparathyroidism, osteoplasty of the altered region was performed. Eight-month follow-up was uneventful.
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