Abstract

Delirium in the intensive care unit (ICU) is a frequent but poorly understood disorder. Most of the concepts regarding the etiology and management of delirium in the ICU have been extrapolated from other populations and case series. ICU delirium seems to be independently associated with worse outcomes, such as prolonged ventilator dependence and ICU stays. Neuroleptics, either alone or in combination with lorazepam, are most commonly used in the management of the symptom of agitation in the delirious patient, but this practice has not been properly evaluated. Studies in non-ICU populations suggest that delirium can be prevented. Evaluation of preventive strategies and management of delirium in ICU patients needs to be targeted for future research to improve outcomes in these patients.

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