Abstract

Many health care workers (HCWs) are potentially at risk for occupationally acquired human immunodeficiency virus (HIV) infection. 1,z Although improved methods of exposure prevention remain the mainstay of further risk reduction efforts, the likelihood that exposures will nevertheless continue to occur has made it necessary for institutions to develop and continually update procedures for postexposure management.-7 This chapter focuses on the management of occupational exposures and discusses issues regarding attempted postexposure prophylaxis with antiviral agents such as zidovudine. Many such incidents also require evaluation and management of possible exposure to other blood-borne pathogens (e.g., hepatitis B and C viruses) and tetanus prophylaxis, as discussed elsewhere.s’9

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