Abstract

Osteonecrosis of the jaws associated with bisphosphonate therapy is characterized as an area of avascular necrosis with an evolution time greater than 8 weeks and without previous history of head and neck radiation. We contribute 2 well-documented new cases of osteonecrosis that affected a male patient and a female patient with a history of oncology therapy using intravenous zolendronate. Lesions were symptomatic and infected bone exposure in the maxilla had a duration of more than 8 weeks, 1 postexodontia and the other 1 post–spontaneous tooth avulsion. The female patient had a good response to the antibiotic therapy and is currently kept under control without pain. The male patient that continued bisphosphonate therapy had a poor prognosis with expansion of bone exposure and spontaneous avulsion of other teeth.

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