Abstract

Routine poison management involves: o I. Stabilization II. Toxidrome recognition III. Decontamination IV. Antidote administration V. Enhanced elimination of toxin VI. Supportive care Stabilization involves airway, ventilation, and circulation support. In the patient with altered mental status, oxygen, naloxone, glucose, and thiamine should be administered. Specific symptom complexes that can be related to specific classifications of toxins are referred to as toxidromes. Emesis by means of ipecacsyrup is rarely used for in-hospital gastric decontamination. Activated charcoal is a useful adsorbent for gastric decontamination. Whole bowel irrigation is useful for iron, lead, lithium, and the body packer phenomenon. Enhancement of elimination may involve multiple dosing of activated charcoal, diuresis (with or without ion trapping), hemodialysis, or charcoal hemoperfusion.

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