Abstract
A lioness was brought for postmortem at the Wild Animal Rescue Centre, Kodanad Kerala India. The right mammary gland was extremely enlarged and was completely invaded by coalescent yellowish granular masses and whitish connective tissue. Histopathology of the organs revealed proliferation of round or polyhydric mild anaplastic cells, with round hyper chromatic nuclei, evident nucleoli and eosinophilic cytoplasm and with moderate anaplasia. The cells formed solid masses surrounded by fine connective stroma. Mitotic figures were conspicuous and in many areas the tumor cells invaded the blood and lymphatic vessels. There were metastatic changes in the retro-mammary lymph node and other organs of the pelvic, abdominal or thoracic cavities with similar characteristics of primary tumor. Key words : anaplastic cells, mammary gland, metastasis
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