Abstract

Malignant sertoli leydig cell tumors of ovary are rare gynecological malignancies. When they present in adolescent age group they pose a management problem with respect to conservative or radical treatment. These tumors are characterized by the presence of testicular elements that produce androgens. Hence, many patients have symptoms of virilization depending on the quantity of androgen production. The decision of management is usually based on surgical staging. Proper counselling is necessary to ensure compliance for chemotherapy. We are presenting a case of a 16 yrs old girl who presented with symptoms of virilization.

Highlights

  • Ovarian Sertoli Leydig cell tumors are rare

  • Case Details A 16 year old unmarried girl presented with the history of amenorrhea since 1 year and excessive hair growth on face, chest, abdomen and limbs since 1 year

  • If poorly differentiated elements or heterologous elements are present, adjuvant therapy may be indicated with radiation or combination chemotherapy

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Summary

Introduction

Ovarian Sertoli Leydig cell tumors are rare. These constitute less than 0.5% of ovarian tumors. Patients with Sertoli-Leydig cell tumors present with signs of defeminization followed by masculinization. Differentiated Sertoli Leydig cell tumor can present a management challenge in young adolescent girls. 2. Case Details A 16 year old unmarried girl presented with the history of amenorrhea since 1 year and excessive hair growth on face, chest, abdomen and limbs since 1 year. Case Details A 16 year old unmarried girl presented with the history of amenorrhea since 1 year and excessive hair growth on face, chest, abdomen and limbs since 1 year Ultrasonography revealed a highly vascular right sided ovarian mass of 10.2 X 9.6 X 6.4 cm size with multiple septations Histopathology report was poorly differentiated malignat Sertoli Leydig cell tumor of right ovary.

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