Abstract
Purpose. Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon in the colorectal tract, and only five such cases have been reported. We present a case of colon MPNST in a teenager who was treated with laparoscopic resection. Case Report. The 17-year-old girl initially presented with right lower abdominal pain and watery diarrhea for two weeks. She had no family history or signs of neurofibromatosis type 1 (NF1; Von Recklinghausen Disease). Abdominal computed tomography revealed a 5 cm mass in the ascending colon causing intussusception, and a laparoscopic right hemicolectomy with primary anastomosis was performed. The microscopic examination showed some spindle cells, and the immunohistochemical staining was positive for S-100 and CD-34 but negative for SMA, desmin, CD-117 and CK. These results support the diagnosis of low-grade MPNST. Conclusions. After laparoscopic surgery, the patient recovered uneventfully and has been disease free for 24 months.
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