Abstract

Only 10 to 15% of adrenal incidentalomas are classified as hyper-functioning. Of functional tumors, the majority are subclinical Cushing’s syndromes, followed by pheochromocytomas and aldosterone producing adenomas. Aldosterone and cortisol co-secreting tumors are rare. Current clinical practice guidelines have limited recommendations regarding the evaluation and management of co-secreting adenomas.

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