Abstract

AbstractMagnetic resonance imaging (MRI) scans for children are a challenge for anesthesiologists since the child must be sedated enough to stand still. But anesthetic drugs used for sedation might have serious side effects and monitorization resources and accessibility to the patient during MRI scan is limited. We retrospectively examined 977 pediatric patients' files who had MRI scans in our hospital. We observed that children received one of the four combinations of anesthetic drugs: group 1 received midazolam, propofol, and ketamine; group 2 received midazolam and ketamine; group 3 received midazolam and thiopental; and group 4 received midazolam and propofol combination for sedation. The patients in group 1 had significantly higher vomiting rates than the patients in group 4 (p = 0.005). We observed bronchospasm in patients in group 1 (p = 0.006) and group 3 (p = 0.001), more than in patients in group 4. Nausea and vomiting ratios were lower in group 4. In patients with nausea and vomiting within a week after the procedure, statistically significant lower neutrophil–lymphocyte ratio values (p = 0.012) were observed. All four anesthetic combinations used in the trial provided safe anesthesia for the children, during the MRI scan. The anesthetic choice must be made according to the procedure time and patient's comorbidities. In this trial, we observed minimum side effects with midazolam and propofol combination.

Highlights

  • The frequency of magnetic resonance imaging (MRI) scans in pediatric patients has increased in recent years.[1]

  • Three patients were excluded from the study because they were unable to be reached by phone for questioning in regard to any complications experienced a week after the procedure

  • The present study retrospectively reviewed anesthetic choices used for sedation during MRI for pediatric patients

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Summary

Introduction

The frequency of magnetic resonance imaging (MRI) scans in pediatric patients has increased in recent years.[1] The MRI has become the preferred diagnostic procedure for many conditions because it is a noninvasive and radiation-free diagnostic procedure. An MRI scan can take $10 to 30 minutes. It is quite noisy, and the patient is moved into a narrow cylinder with limited access.[2] The patient must lie motionless inside a tunnel-like magnetic coil during the MRI scan.[3] Several factors related to MRI can cause fear, agitation, and anxiety in patients, including an unfamiliar environment, the presence of unknown staff, and lengthy scan times.[4]

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