Abstract

The purpose of this work was to evaluate CMR T1 and T2 mapping sequences in patients with intracardiac thrombi and masses in order to assess T1 and T2 relaxometry usefulness and to allow better etiological diagnosis. This observational study of patients scheduled for routine CMR was performed from September 2014 to August 2015. All patients referred to our department for a 1.5T CMR were screened to participate. T1 mapping were acquired before and after Gadolinium injection; T2 mapping images were obtained before injection. 41 patients were included. 22 presented with cardiac thrombi and 19 with cardiac masses. The native T1 of thrombi was 1037 ± 152ms (vs 1032 ± 39ms for myocardium, p = 0.88; vs 1565 ± 88ms for blood pool, p < 0.0001). T2 were 74 ± 13ms (vs 51 ± 3ms for myocardium, p < 0.0001; vs 170 ± 32ms for blood pool, p < 0.0001). Recent thrombi had a native T1 shorter than old thrombi (911 ± 177 vs 1169 ± 107ms, p = 0.01). The masses having a shorter T1 than the myocardium were lipomas (278 ± 29ms), calcifications (621 ± 218ms), and melanoma (736ms). All other masses showed T1 values higher than myocardial T1, with T2 consistently >70ms. T1 and T2 mapping CMR sequences can be useful and represent a new approach for the evaluation of cardiac thrombi and masses.

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