Abstract
The ability to produce composite nanofibers of inorganic particles and synthetic polymers represents a significant advancement in the development of composite materials for potential biomedical applications. In this study, composite nanofibers of magnesium oxide (MgO), poly(ε-caprolactone) (PCL) and chitosan (CS) with diameters in the range of 0.7–1.3 µm were fabricated by electrospinning their blend solutions in trifluroethanol and water. To support the potential use of these nanofibrous membranes for biomedical applications their physicochemical properties such as morphology, mechanical strength, and integrity in aqueous medium, were studied. Cellular compatibility was determined using cell viability assays and microscopy imaging, with the results showing that the nanofibrous membranes support 3T3 cell viability and attachments. The new composite nanofibrous membranes developed in this study have the ability to mimic the physical structure and function of tissue extracellular matrix (ECM) and thus have potential for many tissue engineering applications.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
