Abstract
Adherent or accessory cells, previously indicated as “A”-cells are of paramount importance in the immune response in vitro as well as in vivo. The nonlymphoid adherent population of peritoneal exudate cells, which have phagocytic properties, comprise the accessory cells which have to be present in lymphoproliferative responses in vitro. Most of these cells were obviously macrophages. However, they constitute a heterogeneous population of cells. It appeared that only a minority (8–15%) of these cells bear the Ia determinants of the immune response gene complex (1) which determines their antigen presenting function. Moreover, macrophages may change their properties in this respect during adhesion in vitro (2).KeywordsAccessory CellMononuclear Phagocyte SystemAntigen Present FunctionPeripheral Lymphoid OrganBirbeck GranuleThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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