Abstract
The macrophage activation syndrome (MAS) in its secondary form is known to complicate rheumatic diseases as systemic lupus erythematous (SLE) but rarely realizes a form of revelation.
Highlights
The macrophage activation syndrome (MAS) in its secondary form is known to complicate rheumatic diseases as systemic lupus erythematous (SLE) but rarely realizes a form of revelation.initial MAS, [Pt2] presented with activated CD8 T cells in agreement with persisting MAS –related activation and Tregs were reduced
The aim of our study is to report unrecognized MAS manifestation as an initial symptom of SLE and describe both clinical and immunological characteristics in 4 patients
Main infectious disease causes were ruled out and a diagnosis of MAS was made according to the criteria of HLH 2004
Summary
The macrophage activation syndrome (MAS) in its secondary form is known to complicate rheumatic diseases as systemic lupus erythematous (SLE) but rarely realizes a form of revelation.initial MAS, [Pt2] presented with activated CD8 T cells in agreement with persisting MAS –related activation and Tregs were reduced. Macrophage activation syndrome revealing systemic lupus erythematosus: about 4 cases From 21st European Pediatric Rheumatology (PReS) Congress Belgrade, Serbia. Introduction The macrophage activation syndrome (MAS) in its secondary form is known to complicate rheumatic diseases as systemic lupus erythematous (SLE) but rarely realizes a form of revelation.
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