Abstract
Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016−2017. Direct analyses of swab samples from 10 patients with pertussis revealed a macrolide-resistant mutation, A2047G, in the 23S rRNA. We identified the MT104 genotype of macrolide-resistant B. pertussis (which is prevalent in mainland China) and its variants in these patients.
Highlights
Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016-2017
We identified the MT104 genotype of macrolide-resistant B. pertussis and its variants in these patients
Macrolides are commonly used to treat pertussis, but macrolide-resistant B. pertussis (MRBP) strains have been observed in mainland China and Iran (1–4)
Summary
Taiwan National Infectious Disease Statistics System [cited 2020 Jul 5]. Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan Shibayama); National Institute of Hygiene and Epidemiology, Hanoi, Vietnam (H.T. Duong, A.D. Dang, H.T.T. Hoang); Center for Pediatric Tropical Diseases, National Hospital of Pediatrics, Hanoi (H.T. Do) Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016-2017.
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