Abstract
Lipofibromatous hamartoma of nerve (LFHN) is a very uncommon benign lipomatous tumor with specific clinicopathological characteristics which may present with or without macrodactyly. This tumor-like lesion is composed of fibrous and fatty tissues arising from the epi- and perineurium that surrounds and infiltrates the major nerves and their branches in the body (Enzinger and Weiss 1994). It is believed to be congenital and mainly affects the median nerve in the hand or more rarely the digital nerves at the peripheral level usually well before the third decade (Razzaghi and Anastakis 2005, Jung et al. 2005). An association between this condition and overgrowth of bone and macrodactyly is present in about one-third of cases (Barsky 1967).
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