Abstract
Magnetically separable strontium hexaferrite SrFe12O19 was prepared using the chemical coprecipitation method, and the nanostructured material was characterized by X-ray diffraction, scanning electron microscopy (SEM), energy-dispersive spectrometry (EDS), and BET analysis. The SEM images showed the homogeneity of the chemical composition of SrFe12O19 and uniform distribution of size and morphology. The pore size of the nanomaterial and its specific area were determined by BET measurements. Strontium hexaferrite SrFe12O19 exhibited a strong magnetic field, which is highly suitable in the heterogeneous catalysis as it can be efficiently separated from the reaction. The magnetic nanocatalyst showed high activity and environmentally benign heterogeneous catalysts for the epoxide ring-opening with amines affording β-amino alcohols under solvent-free conditions. When unsymmetrical epoxides were treated in the presence of aromatics amines, the regioselectivity was influenced by the electronic and steric factors. Total regioselectivity was observed for the reactions performed with aliphatic amines. The magnetically SrFe12O19 nanocatalyst showed excellent recyclability with continuously good catalytic activities after four cycles.
Highlights
Introduction β-Amino alcohols are molecules with an interesting role as intermediates in the synthesis of a wide range of biologically active natural and synthetic products [1,2,3,4]. e presence of these functional groups with a defined stereochemistry is of great importance in the biological activity of these molecules. ey are widely used as potential chiral auxiliaries and chiral ligands in asymmetric synthesis [5]. e nucleophilic ring-opening of epoxides with amines represents one of the most important and straightforward methods for the preparation of the β-amino alcohols [6]
As part of our studies directed towards the development of green chemistry protocols by performing organic transformations under solvent-free conditions [41, 42], we have focused our attention on the preparation, characterization, and catalytic application of magnetic strontium hexaferrite SrFe12O19 nanoparticles. e magnetic behavior of SrFe12O19 was evaluated by measurement of the hysteresis loops at room temperature
Rietveld refinement of the sample was performed by TOPAS software in order to define the lattice parameters of SrFe12O19 according to JCPDS 01-084-1531
Summary
Introduction βAmino alcohols are molecules with an interesting role as intermediates in the synthesis of a wide range of biologically active natural and synthetic products [1,2,3,4]. e presence of these functional groups with a defined stereochemistry is of great importance in the biological activity of these molecules. ey are widely used as potential chiral auxiliaries and chiral ligands in asymmetric synthesis [5]. e nucleophilic ring-opening of epoxides with amines represents one of the most important and straightforward methods for the preparation of the β-amino alcohols [6]. Separable strontium hexaferrite SrFe12O19 was prepared using the chemical coprecipitation method, and the nanostructured material was characterized by X-ray diffraction, scanning electron microscopy (SEM), energy-dispersive spectrometry (EDS), and BET analysis. E magnetic nanocatalyst showed high activity and environmentally benign heterogeneous catalysts for the epoxide ring-opening with amines affording β-amino alcohols under solvent-free conditions.
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