Abstract

The authors have studied forty cases of lymphoedema due to Wuchereria bancrofti by means of lymphangiography. They were able to classify the cases according to clinical severity into those without oedema following acute lymphangitic episodes; those showing oedema only after exercise; a further group with permanent oedema; and finally a group with solid oedema and often with skin changes. These clinical groups correlated accurately with increasing abnormalities of the leg lymphatics. The mechanism of oedema is discussed and it is suggested that it is due to widespread perilymphatic fibrosis set up by dead worms. The clinical implications of the lymphographic findings are pointed out. The authors have studied forty cases of lymphoedema due to Wuchereria bancrofti by means of lymphangiography. They were able to classify the cases according to clinical severity into those without oedema following acute lymphangitic episodes; those showing oedema only after exercise; a further group with permanent oedema; and finally a group with solid oedema and often with skin changes. These clinical groups correlated accurately with increasing abnormalities of the leg lymphatics. The mechanism of oedema is discussed and it is suggested that it is due to widespread perilymphatic fibrosis set up by dead worms. The clinical implications of the lymphographic findings are pointed out.

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