Abstract
The authors noted no association between sleep efficiency and either oral corticosteroids or theophylline therapy; however, an insufficient number of patients were evaluated to conclusively prove that sleep quality is unaffected by these therapies. In addition, the Epworth sleepiness scale (ESS) score was not consistent with subjective sleepiness in their cohort; this suggests that although sleep efficiency was reduced, this may not have resulted in any significant subjective complaints of sleepiness. In conclusion, sleep quality impacts quality of life in patients with COPD. This study demonstrates a relationship between IC/TLC ratio and sleep efficiency independent of AHI, which suggests that this ratio may be important in the assessment and treatment of patients with the overlap syndrome. This relationship warrants further investigation, preferably with a prospective study evaluating IC/TLC ratio, sleep efficiency, and patients’ subjective assessments of their sleep quality with intervention.
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