Abstract
BackgroundThe type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms.MethodsThe effect of COVID-19 on lower urinary tract function was studied in a prospective multi-centre, observational study including 238 patients who were admitted with symptoms caused by COVID-19 to the university hospital of Aachen in Germany and Tabriz in Iran.ResultsNone of the patients reported to have any lower urinary tract symptoms. SARS-CoV-2 was found in the urine of 19% of the tested patients.The mortality rate in COVID-19 infected patients with microscopic haematuria together with white blood cells in their urine, was significantly increased from 48 to 61% in the Tabriz cohort (p-value = 0.03) and from 30 to 35% in the Aachen cohort (p-value =0.045). Furthermore, in the group of patients with SARS-CoV-2 urine PCR, the mortality rate rose from 30 to 58%. (p-value =0.039).ConclusionPatients admitted with COVID-19 did not report to have any lower urinary tract symptoms, even those patient who had a positive Urine SARS-CoV-2 PCR.In addition, hematuria, WBC in urine as well as SARS- CoV-2 presence in urine, were found to be strong negative prognostic factors in admitted COVID-19 patients.
Highlights
The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic
The World Health Organization (WHO) revealed the causative virus as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pneumonia as Coronavirus Disease 2019 (COVID-19)
The study population was made up of two cohorts of COVID-19 patients who were hospitalized in the University Hospitals Aachen in Germany and Tabriz in Iran
Summary
The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms. The latest and most momentous threat to our world is the pandemic caused by the new coronavirus (SARSCoV-2). Priorities in medical and surgical healthcare have shifted drastically due to this pandemic. The WHO revealed the causative virus as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pneumonia as Coronavirus Disease 2019 (COVID-19). COVID-19 was declared a pandemic on March 11th 2020 by the WHO [1]. Chest computed tomography (CT) and plain X-ray play a crucial role in the detection of early pulmonary changes and surveillance of patients with COVID-19 [2, 3]
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