Low-dose lithium impact in an addiction treatment setting

Abstract

BackgroundThis study is to assess the effectiveness of low-dose lithium Carbonate (150 mg) augmentation or as a substitute for synthetic antidepressants and antianxiety medications in a residential addiction treatment center. The hypothesis being that adding or using low-dose lithium will improve treatment outcomes on multiple measurable levels. ResultsMarked effects in terms of patient medication usage, safety, and progress along with clinic functioning were recorded. Average opiate MAT dose was reduced by 50%, benzodiazepine usage reduced by 99%, atypical antipsychotics down by 70%, polypharmacy lowered by 79%, and smoking cessation participation increased by 300%. Within the clinic, average census increased by 10%, retention of patients improved by 25%, employment rate and readiness both doubled. Overall program completion improved by 20% while the completion rate of those who took low-dose lithium improved by almost 100%. There were no significant changes in standard lab measurements indicating safety of low-dose lithium usage. ConclusionThe introduction of low-dose Lithium in an addiction treatment setting where trauma, untreated ADHD and medical conditions are common was useful in helping patients achieve and maintain progress in their lives. If further randomized studies confirm what we have seen, the implications could be paradigm shifting.