Abstract
Background and Aims: Low HDL-cholesterol (HDL-C) is associated with a higher risk of chronic kidney disease (CKD) in epidemiological studies and a recent Mendelian randomization study has suggested that genetically higher HDL-C concentration is causally associated with better kidney function. We therefore aim to determine whether HDL-C is associated with rapid kidney function decline in type 2 diabetic patients without overt nephropathy.
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