Abstract
Current functional MRI techniques relying on hemodynamic modulations are inherently limited in their ability to accurately localize neural activity in space and time. To address these limitations, we previously proposed a novel technique based on the Lorentz effect and demonstrated its ability to directly image minute electrical activity with a millisecond temporal resolution in gel phantoms containing conductive wires as well as in the human median nerve in vivo. To better characterize its contrast mechanism and ultimately further improve its sensitivity for in vivo applications, we now apply this technique to image ionic currents in solution, which serve as a better model for neural conduction in biological systems than the electronic currents in conductive wires used in previous phantom studies. Our results demonstrate that ionic currents with durations and current densities on the same order of magnitude as those induced by neuroelectric activity in nerve fibers and in the brain can be detected.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
