Abstract

Long-term outcome of men with lower urinary tract symptoms recruited to the CLasP randomised trial comparing transurethral resection of the prostate, conservative management and laser therapy

Highlights

  • Lower urinary tract symptoms (LUTS) consistent with benign prostatic obstruction become increasingly common with age in men

  • Standard surgical treatment has long been transurethral resection of the prostate (TURP), associated risks of morbidity have led to the development of minimally invasive treatments such as laser therapy, and the increased use of drugs and conservative management (CM)

  • We were able to search the medical notes of 55% of the original CLasP men

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Summary

Summary of research findings Background

Lower urinary tract symptoms (LUTS) consistent with benign prostatic obstruction become increasingly common with age in men. In the UK over 50% of men over the age of 50 have some degree of LUTS and symptoms lead to impairment of quality of life. Between 1994 and 1996, 570 men diagnosed with LUTS were recruited to one of three linked CLasP trials. Trial B recruited 82 men with chronic retention and Trial C 148 men with acute retention. Those in Trials B and C were randomised to TURP or laser. Long-term data were, and remain, lacking in this important clinical area. This current study provides long-term followup of between 13-15 year

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