Abstract
Background: Several studies show that early exposure to pesticides and during the preschool and school stage affects the development and health of children. In Maule, a series of studies have shown the exposure of organophosphate pesticides(OP), however, there are no studies assessing exposure to pyrethroids and herbicide 2,4 D. Objetive: To evaluate exposure to pyrethroids 3-phenoxybenzoic acid 3-PBA, trans-2,2-(dichloro)-2-dimethylvinylcyclopropane carboxylic acid trans-DCCA(Trans-TCC) and 2,4 D herbicides in schoolchildren. Method: Longitudinal study, 48 schoolchildren from 5 to 13 years old from two rural schools in the Maule. Specific metabolites of pyrethroids 3-PBA, Trans-TCC and 2.4 D in the urine of the school children were evaluated. The data were correlated with an earlier study that evaluated the exposure of OP metabolites. Two samples were taken in September and 2 samples in November, a total of 384 urine samples were obtained during 2016 and 2017. Data analysis: descriptive, U Mann Whitney for repeated measurements, Spearman and GEE. Results: The 100% of schoolchildren have more than two pesticide metabolites in their urine in both years, with the 3-PBA metabolite being the most frequent. 3-PBA in November 2017 increases its presence in urine compared to 2016(from 0.69 μg/L in 2016 to 1.90μg/L in 2017). In 2016, the specific metabolites of 3-PBA correlate with TCC, 2,4 D, chlorpyrifos, diazinon, paration. In 2017, 3-PBA was correlated with 2,4 D and TCC. Importantly, the concentrations of 3-PBA pesticide metabolites in urine found in Chilean children was higher than studies in the USA where there is an association of exposure from prenatal stage to these metabolites with difficulties in emotional control and attention. Conclusions: Promote the monitoring, training and active epidemiological surveillance of agricultural communities. The increased use of pyrethroids is worrying. Promote the intervention of school communities, involving government agencies and agricultural companies, considering preventing to the population.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
