Abstract
Immunohistochemical staining of placental tissue for β-endorphin immunoreactivity was positive in the syncytiotrophoblast in both early and term pregnancy. Cation-exchange liquid chromatography and radioimmunoassay revealed peaks of β-endorphin and β-lipotrophin and a third immunoreactive peak of unknown nature. The concentration of β-endorphin was higher in the placental tissue than it was in the maternal or cord plasma. β-Lipotrophin was not detected in all placentae studied. We did not find any effect of gestational age on tissue concentrations of endorphins in the placenta, nor was there any significant difference in the placental endorphin content between placentae collected at elective caesarean section before labour and after spontaneous vaginal delivery.
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