Abstract
This study evaluates the effect of local infiltration analgesia with bupivacaine and adrenaline on perioperative blood loss in total hip arthroplasty. Patients who had primary total hip arthroplasty were retrospectively assigned to two groups. One group had 100 ml of bupivacaine/adrenaline solution injected into periarticular soft tissues at the end of the procedure. There were 55 patients in the infiltrated hip group and 44 patients in the not infiltrated group. Patients' hemoglobin level (Hb), hematocrit (HTC), red blood count (RBC), platelet count (PLT) and International Normalized Ratio (INR) as well as the need for blood transfusions were compared statistically between groups preoperatively and postoperatively. There were no significant differences between Hb, HTC or RBC levels as well as the rate and amount of blood transfusions on the 1st, 4th postoperative days or at patients' discharge between infiltrated and not infiltrated groups. This study does not support the hypothesis that the use of local infiltration analgesia with adrenaline may reduce perioperative blood loss in total hip arthroplasty.
Highlights
Hip arthroplasty is one of the most common orthopedic surgeries performed worldwide [1,2,3]
Adrenaline in this solution has proven to have an additional benefit of decreasing perioperative blood loss and transfusion rates in total knee arthroplasty [10], especially when used together with tranexamic acid [11]
There were no significant differences between hemoglobin level (Hb), HTC or red blood count (RBC) levels on Day 1, Day 4 or at patients’ discharge between infiltrated and not infiltrated groups (Table 3)
Summary
Hip arthroplasty is one of the most common orthopedic surgeries performed worldwide [1,2,3] It is an extensive procedure with a range of associated problems, including pain and significant blood loss, among other [1, 3, 4]. A range of different solutions of regional anaglesics are used diluted in normal saline [4], with or without addition of adrenaline. Adrenaline in this solution has proven to have an additional benefit of decreasing perioperative blood loss and transfusion rates in total knee arthroplasty [10], especially when used together with tranexamic acid [11]. Local infiltration analgesia with adrenaline has proven to be beneficial
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
