Local Cellular Faults in Inflammation in the Diabetic—Failure of Glycogen Transport.

Abstract

s1 May 1967Local Cellular Faults in Inflammation in the Diabetic—Failure of Glycogen Transport.John W. Rebuck, M.D., Ph.D., Fred W. Whitehouse, M.D., F.A.C.P., F. Robert Neher, M.D., Klaus F. Lang, M.D.John W. Rebuck, M.D., Ph.D.Search for more papers by this author, Fred W. Whitehouse, M.D., F.A.C.P.Search for more papers by this author, F. Robert Neher, M.D.Search for more papers by this author, Klaus F. Lang, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-5-1060_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe diabetic is allegedly more susceptible to infection than the nondiabetic. We have studied the local cellular reaction to inflammatory stimuli in the diabetic in an attempt to elucidate this problem.Using our skin window technique to study the cellular reaction to stress, we performed 76 test lesions in 37 diabetic patients. Local stimuli included insulin (24 lesions), a suspension of killed Escherichia coli (16 lesions), and diphtheria toxoid (36 lesions). Appropriate control studies have been done. The cellular exudate was stained by the Leishman and periodic acid-Schiff (PAS) techniques.Quantitatively, the cellular response in the diabetic did not differ... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, Michigan PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1967Volume 66, Issue 5Page: 1060-1061 Issue Published: 1 May 1967 PDF DownloadLoading ...