Abstract

Background&Aims: Patients with advanced fibrosis related to nonalcoholic fatty liver disease(NAFLD) are at risk of developing hepatic and extrahepatic complications. Liver stiffness measurement(LSM)by FibroScan has a good diagnostic accuracy for advanced fibrosis and can also predict the occurrence of liver-related events in patients with chronic hepatitis C.Data about the accuracy of LSM in the prediction of events in NAFLD,especially in patients with NAFLD and F3-F4 fibrosis,are scarce. We investigated whether,in a large cohort of patients with NAFLD and compensated advanced chronic liver disease(cACLD),LSM at baseline,at follow-up,and its variations are accurate for the prediction of hepatic and extrahepatic events.

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