Abstract

The article is based on the study and comparison of surgical interventions on the large intestine for neoplasms. The aim of the study: to investigate and compare surgical interventions based on the efficacy, safety of mixed endoscopic surgeries and laparoscopic surgeries not subject to endoscopic removal of neoplasms. 17 randomized prospective and retrospective observations were selected for this work, the observations were divided into two groups, the first group of patients who underwent surgical intervention by hybrid laparo-endoscopic method and the second group of patients who underwent laparoscopic resection of the colon. The total number of patients amounted to 835 (100%) of which 517 (61,9%) were included in the first group and the second group consisted of 318 (38,1%) patients. The results of the study showed that in the first group the duration of the operation and the patient’s stay in hospital were statistically significantly shorter than in the second group (mean difference = -38.7 minutes; 95% CI -51.4 -26.0; p < 0.00001, bed-day mean difference = -2.3 days; 95% CI -3.17 - -1.57; p < 0.00001). And in terms of the incidence of postoperative complications, recurrence and mortality, no significant differences were observed between the groups (p = 0.05). Patients who underwent hybrid laparo-endoscopic surgeries with benign endoscopically unresectable colorectal neoplasms do not increase the incidence of postoperative complications and lethality. The advantage of this method is the reduction of bed-days and duration of the operation also time.

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