Abstract

Phase Separation Liquid–liquid phase separation of protein in all-aqueous environment is thought to be related to functional and aberrant biology, and has the potential to conceptualize smart biomaterials. In article number 2008670, Tuomas P. J. Knowles and co-workers use protein microgel precursors to form liquid–liquid phase-separated systems with size-adjustable and dispersity-tunable biomolecular condensates. The outcomes at water–water interfaces can shed light on the understanding of biophysics in relevant areas and inspire the applications in bioengineering and biomedicine.

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