Abstract
Lipid profile is changing with changing developmental status and lifestyle in less developed countries and coronary artery disease risk factor is rising. The aim of the study is to find the lipid pattern in Department of Medicine in tertiary care hospital. An observational prospective study was conducted in 408 subjects from January 2009 to February 2010. Study subjects were selected irrespective of co-morbid condition and coronary risk factors. The mean triglycerides, cholesterol, LDL, HDL were 138.3 +/- 78.3 mg/dl, 180.2 +/- 53.7 mg/dl, 113.8 +/- 41.2 mg/dl, 40.1 +/- 10.1 mg/dl respectively. The Triglycerides (>140 mg/dl), Cholesterol (>250 mg/dl), LDL (>92 mg/dl), HDL (<45mg/dl) were 35.5%, 7.6%, 67.9%, 76% respectively. Lipid profile is becoming atherogenic with high triglyceride, high LDL and low HDL being the most common abnormality. An epidemiological study is recommended to understand the true burden of the disease in the community.
Highlights
INTRODUCTIONIn Western countries, it has been shown that coronary heart disease (CHD) is related to high serum total cholesterol (TC) levels.[1]
Lipid profile is changing with changing developmental status and lifestyle in less developed countries and coronary artery disease risk factor is rising
Lipid profile is becoming atherogenic with high triglyceride, high LDL and low HDL being the most common abnormality
Summary
In Western countries, it has been shown that coronary heart disease (CHD) is related to high serum total cholesterol (TC) levels.[1]. With growing urbanization and industrialization in Asia, it has been shown that there is a concomitant rise in the level of serum TC and with it a rise in CHD. 1,2 Similar pattern of rise has been observed in Southeast Asian region with a slow progress towards the suburban and rural area.[2,3,4] Studies correlating with coronary risk factor and lipid profile in our setup are few with some study suggesting high total cholesterol and LDL as the common abnormality and some correlating with adverse cardiac outcome.[5,6,7,8,9] The objective of the study is finding the lipid pattern in Kathmandu University Teaching Hospital
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