Abstract
Nanoemulsion (NE), solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) were produced using hot high-pressure homoge nization method (HPH) and characterized by photon correlation spectroscopy (PCS), differential scanning calorimetry (DSC), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The mean particle sizes of all prepared nanocarriers were in the range of100-150 nm and influenced by the lipid composition. The obtained results of DSC and XRD studies confirmed that the incorporation of liquid lipid into the nanoparticles resulted in the formation of less ordered crystalline lattice. The release rate at the burst release stage could be accelerated by decreasing the liquid lipid ratio. The retention amounts of resveratrol in the skin also depended on the lipid composition. The results showed the potential of lipid based nanocarriers, particularly those with high soild lipid ratio, for topical delivery of resveratrol.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.