Abstract
A DNA polymorphism has been found in the 3′ untranslated region of the carbonyl reductase gene (CBR). Genotypes of the members of the CEPH pedigrees have been obtained and used in linkage analysis to map the CBR gene in the linkage map of human chromosome 21. The gene maps between the interferon-α receptor (IFNAR) and the D21S55 loci.
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