Abstract

Revascularization endodontic procedures commonly require multiple treatment sessions. However, single visit procedures may be advantageous from the clinical and patient management standpoints. The purpose of this review was to evaluate the outcomes of single-visit revascularization endodontic procedures for the management of immature permanent teeth with non-vital pulp. Two electronic databases (Scopus and PubMed) were searched, from their inception to July 2018, for studies that assessed clinical and/or radiographic and/or histologic outcomes of single-visit revascularization endodontic procedures performed in immature permanent teeth with non-vital pulp. Case reports, animal studies and clinical trials were included. The quality of case reports was appraised by Joanna Briggs Institute Critical Appraisal Checklist for Case Reports. The quality of randomized clinical trials was assessed by the revised Cochrane risk of bias tool for randomized trials. The risk of bias for animal studies was assessed using SYRCLE's risk of bias tool. Tabulation followed by narrative synthesis was used to draw conclusions. Seven studies satisfied the selection criteria. Five were classified as case reports, one as a randomized clinical trial and one as animal study. The latter presented with a high risk of bias, whilst the remaining showed a low risk. The evidence supporting the potential use of single-visit revascularization endodontic procedures is scarce. Successful single-visit revascularization endodontic procedures commonly include the use of high concentrations of sodium hypochlorite and EDTA combined with the use of agitation systems. Further clinical trials with long term follow up are needed to confirm the results of the current review.

Highlights

  • Trauma or caries in immature permanent teeth can result in necrosis of the pulp and cessation of the root development process, leaving thin and fragile root canal walls [1]

  • Main characteristics of the included case reports, clinical trial and animal study were reported in Tables 1, 2 and 3 respectively

  • The current review aims to obtain a narrative integration of the relevant evidence regarding the outcome of single visit revascularization endodontic procedures (REPs) for the management of immature permanent tooth

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Summary

Introduction

Trauma or caries in immature permanent teeth can result in necrosis of the pulp and cessation of the root development process, leaving thin and fragile root canal walls [1]. Non-vital immature teeth are associated with a high risk of root fracture, because of their inability to sustain physiological mastication forces and further trauma [1]. The management of immature permanent teeth with a non-vital pulp is a demanding procedure for clinicians [2,3]. Whilst calcium hydroxide multi-visit apexification and apical barrier techniques are not associated with further root maturation [8], REPs are associated with root length and wall thickness increased together with reduction in apical diameter [8]. The aim of this root maturation is to reduce the risk of tooth fracture

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