Abstract
Nitrogen mustard (methyl bis chloroethylamine hydrochloride), a radiomimetic and cytotoxic agent, has proved to be also a powerful teratogenic agent. When administered to vertebrate embryos at a particular stage of development and at doses which allow survival of the embryo, nitrogen mustard produces a very similar type of malformation in different animal species. Limb malformations were obtained in amphibians, mammals and birds (1,2).
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