Abstract
Introduction: Our aims were to investigate whether life course socioeconomic position (SEP) is associated with subclinical atherosclerosis, and whether this association is partially mediated by job stress. Methods: We used the baseline data of 8,830 current workers from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Subclinical atherosclerosis was assessed by carotid intima-media thickness (IMT). Maternal education, social class of first occupation, and occupational social class were used to measure childhood, youth and adulthood SEP, respectively. We evaluated the job strain following the Karasek's model and job control was also analyzed separately. Directed acyclic graph, and linear regression models were used. Results: Maternal education was not associated with IMT in men, but low versus high maternal education was associated with higher IMT in the order of 0.022mm (p
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