Abstract
To the Editor: It is well established that statins improve the prognosis of patients with coronary artery disease. However, it is still unclear whether the protective effects of statins relate to lipid lowering only or whether other so-called pleiotropic effects may contribute. Experimental data support the pleiotropic effects of statins, but knowledge on their clinical relevance is limited. We read with great interest the recent article by Liu et al.1 The authors compared the effect of simvastatin 40 mg/d, and the combination of simvastatin 10 mg and ezetimibe 10 mg …
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