Abstract
Yeast species from which respiratory deficient, or petite, mutants cannot easily be obtained (petite negative species) give rise to micro-colony-producing mutants when subjected to an acriflavine treatment that induces the production of petite mutants in several other yeasts (petite positive species). As a rule, the micro-colonies die before becoming visible to the naked eye. Sometimes they can be subcultured and the respiratory deficiency of the mutants can then be demonstrated. The results of growth experiments under anaerobic conditions suggest that the functioning of a respiratory system is more important to the petite negative yeasts than it is to the petite positive yeasts. An incidental lethal side-effect of acriflavine, specifically on petite negative yeasts, is improbable since mutagenic treatment with supraoptimum temperatures induced viable petite mutants in petite positive yeasts only, and again a lethal mutation in petite negative yeasts.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
