Abstract

In addition to his versatility in painting and art, Leonardo da Vinci was extremely passionate about medicine, particularly the study of the brain. He investigated the ventricles of the brain in great detail in an attempt to locate the seat of the soul in the brain (senso comune). Pathography on Leonardo da Vinci suggests that his ability to use mirror writing and supposed attention-deficit/hyperactivity disorder may have contributed to his extraordinary creativity and tendency to be unable to complete his work. It is presumed that Leonardo da Vinci died of a stroke; however, it is speculated that ulnar or median nerve palsy led to right upper limb paralysis that prevented him from painting in his later years.

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