Laser applications in peri-implantitis therapy: A narrative review.

Abstracts from the World Federation for Laser Dentistry—Asia Pacific Division Virtual Conference July 16–17, 2021

Abstracts from the 7th Congress of the World Federation for Laser in Dentistry European Division June 20–22, 2019 Parma, Italy

Introduction: The use of lasers in dentistry has evolved significantly, becoming integral to various diagnostic and therapeutic procedures. The aim of the present study is to conduct a quantitative and qualitative analysis of scientific production on the application of lasers in dentistry in the Web of Science database over the past decade. Methods: This is a scientometric study evaluating scientific documents indexed in the Web of Science database in the field of laser applications in dentistry up to the end of 2023, using quantitative and qualitative indicators. Data analysis was conducted using Excel and VOSviewer software. Results: The graphs for article and citation growth showed a steady and steeper upward trend over the past ten years, respectively. The countries with the highest production, ranked first to third, were Brazil, the USA, and China, with the top two institutions also located in Brazil. The most prominent journals publishing studies on laser applications in dentistry, in order, were Journal of Prosthetic Dentistry, Clinical Oral Investigations, and BMC Oral Health. Aoki was the most-cited author, with 230 citations in a Q1 journal from Japan, though ranked sixth in terms of production. The highest scientific collaborations were observed in the USA, followed by Brazil and China. Although the Journal of Periodontology ranked ninth in terms of the number of publications, it ranked first in co-citation. In terms of thematic keyword analysis, six clusters were identified: low-power laser and photodynamic therapy in dentistry, antibacterial properties of laser in dentistry, laser applications in implant treatment, laser use in restorative treatments, laser applications for dental caries prevention, and laser use for pulp vitality assessment. Conclusion: Researchers should stay regularly informed of ranking results to make more accurate decisions in research and clinical practices. Therefore, given these findings and the importance and saturation of various topics and their applications in dental practices, there is a need for institutions and researchers to reassess research priorities.

Gastrointestinal Laser Endoscopy—Future Horizons

Photodynamic Therapy for Urological Malignancies: Past to Current Approaches

Talaporfin Sodium–Mediated Photodynamic Therapy Alone and in Combination with Pulsed Dye Laser on Cutaneous Vasculature

One of the basic purposes in dental treatment is providing a painless treatment for patients. This purpose may be achieved by the application of laser in dentistry. Low-level laser therapy (LLLT) is an internationally accepted title for biomodulation with low-level lasers which we use to achieve ideal therapeutic effects. Low-level laser therapy is a painless, reproducible, non-invasive, and without need of anesthesia treatment which is used to treat a variety of pain syndromes, injuries, wounds, fractures, neurological conditions and pathologies. Laser therapy works on the principle of inducing a biological response through energy transfer. The parameters that used in laser therapy determine the effective depth of penetration. We can mention anti-inflammatory effects, stimulation of wound healing, stimulation of immune system, increase of blood flow and activation of vasodilatation, increase of cellular metabolism and analgesic effects as advantages of the application of this type of laser. The aim of this review study was to evaluate the effect of low-level laser

Introduction Dental implants are widely used for the restoration of edentulous or partially edentulous areas of the mouth. Despite their high success rate, complications such as peri-implantitis can occur, jeopardizing implant stability. While mechanical debridement remains the standard treatment, recent evidence has suggested that adjunctive laser therapy, including photodynamic and low-level laser therapy, may offer improved outcomes. This systematic review aimed to evaluate the efficacy of laser therapy combined with mechanical debridement compared to mechanical debridement alone in the treatment of peri-implantitis. Materials and Methods A systematic review search was conducted in accordance with the 2020 PRISMA protocol. The search included articles published between 2019 and 2024 in English, retrieved from PubMed, Scopus, and ScienceDirect databases. After exporting the results into Microsoft Excel, articles were screened based on their titles, abstracts, and full texts to determine relevance. Only studies comparing laser-assisted therapy with conventional mechanical debridement in the context of peri-implantitis were included. Results A total of 90 articles were initially identified. After screening and applying the inclusion criteria, 5 studies were selected for the final analysis. These studies consistently demonstrated that adjunctive laser therapy resulted in greater improvements in clinical outcomes, including reductions in probing depth, plaque index, bleeding on probing, and bone loss, when compared to mechanical debridement alone. Discussion The findings of this review suggested that laser therapy, when used in conjunction with mechanical debridement, offers enhanced clinical benefits in managing peri-implantitis. The anti-inflammatory and bactericidal properties of photodynamic and low-level laser therapies appear to contribute to improved tissue healing and infection control. However, the included studies varied in terms of laser protocols, treatment durations, and follow-up periods, limiting the generalizability of the results. Standardized methodologies and longer-term follow-up are needed to validate these outcomes further and define best practices. Conclusion Combining laser therapy with mechanical debridement appears to be a more effective treatment strategy for peri-implantitis than mechanical debridement alone. This approach shows promise in reducing inflammation and promoting healing. Nonetheless, further high-quality research is necessary to confirm long-term benefits and establish clear clinical guidelines for its use.

Consensus Agreement on the Design and Conduct of Clinical Studies with Low-Level Laser Therapy and Light Therapy for Musculoskeletal Pain and Disorders

The effects of low-level laser therapy and photodynamic therapy on oral health of fixed orthodontics patients. A systematic review and meta-analysis

Aim:Peri implant diseases lead to pathological changes in the peri implant tissues and loss of osseointegration. The purpose of this analysis is to evaluate the effect of various lasers and photodynamic therapy (PDT) on peri implant diseases compared to conventional procedures.Setting and Design:This meta analysis was conducted as per the Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines.Materials and Methods:A systematic search of the electronic databases such as PubMed, ICTRP, CT.gov, Embase, and Cochrane Library was done additional to manual search of peer review article on peri-implant diseases. Eleven randomized control clinical trials were included in which laser therapy and PDT were used as an interventional procedure.Results and Statistical Analysis Used:Review Manager 5.03 (RevMan, Nordic Cochrane Center, Copenhagen, Denmark), and random effects model were used to assess mean difference (MD). Bivariate differential mean statistic was used in intergroup estimate with 95% confidence interval (CI). I2 test statistics was applied for heterogenity and P < 0.05 was considered significant statistically. The literature search yielded a total of 113 articles among which 11 articles were included for quantitative analysis. The selected outcome PD reported MD −0.01 with 95% CI (−0.13, 0.16), P = 0.84, and CAL reported MD −0.09 with 95% CI (−0.32, 0.14), P = 0.45, respectively.Conclusion:Laser treatment as an adjunctive therapy or monotherapy in peri implantitis does not show any superior effects than conventional measures as per evidence. However, cases with peri implant mucositis have shown far more promising results with laser therapy compared to peri implantitis.

Low-level light/laser therapy versus photobiomodulation therapy.

In recent years, there has been a growing interest in the use of dental lasers for treatment of periodontal diseases. The purpose of this short-term clinical trial was to evaluate the effects of a combination of photodynamic therapy with low-level laser therapy as an adjunct to nonsurgical treatment of chronic periodontitis. Twenty-four nonsmoking adults with untreated chronic periodontitis were randomly assigned in a split-mouth design to receive scaling and root debridement with or without one course of adjunctive photodynamic therapy and low-level laser therapy within 5 d. Plaque, bleeding on probing, probing depth and gingival recession were recorded at baseline, 1 and 3 mo after the treatment. Gingival crevicular fluid was collected for assay of interleukin-1β levels at baseline, 1 wk and 1 mo. The test teeth achieved greater reductions in the percentage of sites with bleeding on probing and in mean probing depth at 1 mo compared with the control teeth (p < 0.05). A significant decrease in gingival crevicular fluid volume was observed in both groups at 1 wk (p < 0.001), with a further decrease at 1 mo in the test sites (p < 0.05). The test sites showed a greater reduction of interleukin-1β levels in gingival crevicular fluid at 1 wk than the control sites (p < 0.05). No significant differences in periodontal parameters were found between the test and control teeth at 3 mo. The present study suggests that a combined course of photodynamic therapy with low-level laser therapy could be a beneficial adjunct to nonsurgical treatment of chronic periodontitis on a short-term basis. Further studies are required to assess the long-term effectiveness of the combination of photodynamic therapy with low-level laser therapy as an adjunct in nonsurgical treatment of periodontitis.

Comprehensive Periodontal Therapy: A Statement by the American Academy of Periodontology

To evaluate the efficiency of therapeutic Ultrasound, low level laser and compression therapy for healing of venous Leg ulcers and Compare the effect of modalities on the ulcers. Three groups were included in the study. Group I: 20 patients with leg ulcers treated with low level laser therapy. Group II: 20 patients with leg ulcers treated with ultrasound therapy. Group III: 20 patients with leg ulcers treated by compression therapy (four layer bandage) were used in this study. All patients were subjected to detailed history, clinical evaluation in addition to X-ray of legs and feet, and Doppler ultrasound of both legs. The main variables for follow up were the measurement of the area of the lesions under aseptic conditions at 0, 1, 2, 3 months and qualitative clinical evaluation of the ulcers by physician and by the patient. The results from group I, group II and group III were obtained and then compared with each others. According to the size of the ulcer, some ulcers heal within 1 month which is (15.6%) in group I, (10%) in group II, and (28.5%) in group III. Some ulcers heal within 2 months which is (28%) in group I, (23.3%) in group II and (37%) in group III. The remaining ulcers heal within 3 months or more which are (56%) in group I, (66.6%) in group II and (34.2%) in group III. Thus the percentage of healing denoting that compression bandage technique used in group III is the most efficient in healing of chronic venous leg ulcer followed by laser therapy and lastly US therapy (P = 0.04 at the end of the first month and P = 0.03 at the end of the third month). Compression therapy is the most efficient treatment of venous leg ulcers. Low level laser therapy and Ultrasound therapy are useful methods as a conservative treatment of venous leg ulcers and can be used in ulcers of small size.