Abstract
Jussiaea repens (L.) leaf ethanol extract (LEE) and its major phyto-compound (MPC) have effects against larvae and adults of dengue, malarial, and filarial vectors. Total larval death rates were recorded from LEE and MPC has significant larval killing activity with LC50/LC90 values of Ae. albopictus, An. stephensi, and Cx. quinquefasciatus that were 118.3/229.9, 116.1/216.8, 114.4/213.5 and 17.7/27.5, 15.6/25.4 and 12.3/21.1μg/ml, respectively. A best repellent activity was ascertained at 3.057mg/cm2 concentration of LEE and MPC provided 100% protection upto 240min against selected human vector mosquitoes (HVMs). The functional groups were confirmed by FT-IR analysis and their presence in ethanol extract and mass spectral analysis: 4-piperidineacetic acid, 1-acetyl-5-ethyl-2-[3-(2-hydroxyethyl]-1H-indol-2-yl]-á-methyl-, methyl ester compound was identified in the LEE. The results obtained suggest that J. repens LEE and its MPC were important and responsible for health protection and control of HVMs.
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