Abstract
14 cases of dermatopathic lymphadenitis were studied by light and electron microscopy. In two instances the ATP-ase reaction was applied to lymphoid tissue. The main morphologic feature of dermatopathic lymphadenitis is an extreme enlargement of the thymus-dependent area which is due to a large number of closely connected, interdigitating reticulum cells (IDC). Enzyme-histochemically IDC are ATPase positive. In all systematically studied cases Langerhans cells are found in the paracortex. They may also be present in the sinuses and the neighbouring lymph node parenchyma. Like IDC, Langerhans cells have an irregularly shaped nucleus, numerous cytoplasmic processes as well as invaginations; in the paracortical area they show intimate connections with each other or with IDC. Frequently they can be differentiated from IDC only by the presence of Langerhans granules. The close topographic apposition to T-lymphocytes typical of IDC is also true of Langerhans cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
