Abstract
Langerhans cell histiocytosis (LCH) is a rare monoclonal disorder of dendritic cells originating from bone marrow. We are reporting two cases of isolated involvement of ocular region both of which clinically appeared as soft tissue tumour. A young girl of two and half years presented with swelling of left eyelid. Microscopic examination of biopsy showed collections of round cells which were large having abundant cytoplasm and centrally placed nuclei. Plenty of eosinophils were seen in the background. The final diagnosis of LCH involving eyelid was given after histopathological examination. Second case report is of three-year-old girl presented to ophthalmology outpatient department with the complaints of painless progressive swelling of lateral aspect of left orbital wall for four months which were rapidly increasing in size for the past two months. Fine-needle aspiration (FNA) of both swellings was done and finding was suggestive of LCH. The final diagnosis of LCH was given on histopathological examination of biopsy tissue from both the swellings. Ocular region involvement by Langerhans cell histiocytosis is a very rare presentation.
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