Abstract
The relative rates of ferric ion removal from human milk lactoferrin and human serum transferrin by the synthetic tricatecholate sequestering agent N,N',N''-tris(5-sulfo-2,3-dihydroxybenzoyl)-1,5,10-triazadecane (3,4-LICAMS) have been compared at pH 7.4 and 37 o C. Hyperbolic plots of the observed pseudo-first-order rate constants with increasing concentrations of 3,4-LICAMS were obtained for both proteins and are consistent with a similar mechanism of iron removal from both proteins by this ligand. However, the average limiting rate of iron removal from milk lactoferrin (k max =6.5(4)×10 -4 min -1 ) is about 100-fold slower than that found from serum transferrin (k max =6.3(4)×10 -2 min -1 ) under the same conditions
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
