Abstract
A new radioisotopic labelling method of two antacid preparations containing magnesium and aluminium ions has been designed. 99mTc-pyrophosphate was used as tracer agent and, owing to the high labelling efficiency obtained (> 98%), no purification step was necessary. The stability of both labelled antacids was tested as well as their antacid capacity and their protein-binding capacity compared with the unlabelled samples. All these tests were satisfactory enough to consider this 99mTc labelling method a good tool for preparing labelled antacids that contain A1 3+ and/or Mg 2+ and so to evaluate the antacid gastric emptying pattern by means of scintigraphic studies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
