Abstract
Artificial inductors have been developed to study qualitatively and quantitatively the phagocytosis of nonliving particles by Amoeba proteus. The experimental system includes nylon microcapsules, ion-exchange particles, and treated glass beads. Our results show that there are two fundamental mechanisms of phagocytosis in A. proteus. The first mechanism, related to the ingestion of living prey or particles that diffuse chemotactic substances, involves biphasic activity of the chemotactic substances. The second mechanism, in connection with insoluble particle phagocytosis, involves the presence of a positive charge at the surface of the particle.
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